Buy Accutane Online - Indications for Oral Acne Therapy
Accutane is the first-generation retinoid, which is used to treat acne. Patients with mild to severe acne are prescribed Accutane soft gelatin capsules that contain 10 mg, 20 mg or 40 mg of Isotretinoin. This active ingredient suppresses the production of sebum and thus reduces the size and amount of acne on the face and body.
Indications for oral acne therapy
Accutane capsules may be prescribed to several groups of patients. Appropriate candidates for its use are adolescent patients aged 12 and older, and adults:
- with severe recalcitrant nodular acne.
Accutane should be prescribed for the treatment of acne in those patients, who can not improve the skin appearance with the help of over-the-counter acne medications and/or antibiotics.
Accutane does not possess an antibacterial activity. The mechanism of its action is not fully understood, but it is reliably known that the use of Accutane capsules promotes:
- reduction in skin inflammation
- acne development cessation
- acceleration of skin regeneration
Proper use of Accutane allows curing acne and minimizing the risks of permanent scars.
As a retinoid, Accutane accts through:
- Providing an anti-inflammatory effect.
- Reducing the size of the sebaceous glands.
- Suppression of secretory activity of the sebaceous glands.
Accutane works efficiently, you should not expect immediate relief of acne. The course of treatment should continue, even if the skin has cleared up. At the beginning of the treatment, acne may worsen for a while, after which the symptoms will improve and the remission of the skin disease will begin.
How do I take Accutane for the first time?
The dermatologist will give you precise instructions on how long and how many capsules should be taken. The usual dose of Accutane is 0.5 mg/kg per day for up to 28 days. The dose can be gradually increased to:
- mg/kg - is the usual dose for most patients.
- mg/kg - is a dose for the treatment of very severe acne.
The daily dose of Accutane is usually introduced in two separate doses. Food increases the bioavailability of the active substance by a factor of 2, which increases the anti-inflammatory effect. Always take Accutane capsules with food.
As a rule, near-complete or complete suppression of nodular acne can be noticed after 12-24 weeks of therapy. Usually, within several months after the termination of the first treatment course:
- No new lesions appear.
- Cosmetic skin improvement takes place.
Patients may be prescribed repeated courses of treatment, but not earlier than 2 months after the completion of the previous one. Although, the majority of patients will only need one course of treatment to achieve remission, if they observe all recommendations for use.
Who should not use Accutane?
Accutane is suitable for most patients with severe nodular acne, but not for everyone. The oral anti-acne drug Accutane is contraindicated in the following cases:
- Use of antibiotics from the tetracyclines class.
- Acute or chronic vitamin A toxicity.
- Renal or hepatic insufficiency.
- Hypersensitivity to Isotretinoin.
- Very high level of lipids in the blood.
Pregnancy and lactation are a contraindication for oral acne therapy with Accutane capsules. In addition, women should not breastfeed and get pregnant within one month after the treatment discontinuation.
Accutane has a high potential to adversely affect fetal or infant development. Therefore, you should not be a blood donor within 30 days after the course of treatment. If such blood is transfused to pregnant women, it may become a risk for the fetus.
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